In order to design an advanced Pulsed Detonation Engine (PDE),the effects of fuel types on its performance were investigated.In the investigation,gasoline,kerosene,ethyne and hydrogen were taken as the fuel and the oxidizer is air.The PDE model was designed by authors.The performance of PDE,such as averaged thrust,specific impulse and specific fuel consumption,were calculated and analysed respectively with each type of fuel.The gasoline/air mixture was tested in PDE model to verify the calculating method.The experimental results were consistent with the calculated ones on the whole,so that the conclusion drawn from the calculated results can serve as theoretical foundation for reasonable selection of the fuel.