The stress rupture equation with high reliability is an important basis in the design of the mechanism working in high temperature environment.But the stress rupture equations with high reliability and confidence obtained by using the traditional method can not satisfy the specified reliability and confidence.So the creep rupture strength and creep life predicted is overestimated.Therefore,a new stress rupture equation with high reliability and confidence is derived,which overcomes the shortcomings in the current method.This equation can accurately predicted the creep rupture strength and creep life with high reliability and confidence.