In this paper we analyze the relation between fault diagnosis and data fusion,and summarize the correlative techniques of leak detection.In order to make up the shortage of information for leak fault diagnosis,we integrate multi-sensors,such as the dotted sensors and the infrared sensors,to detect the phenomena caused by the leak,and then the system based on data fusion for diagnosing the leak of LRE is established.The approach can enhance the validity and reliability of leak fault diagnosis.