Volume 36 Issue 6
Jun.  2021
Turn off MathJax
Article Contents
Article Navigation >  Journal of Aerospace Power  > 2021  >  36(6): 1304-1314
XIE Nan, TANG Yumeng, LIU Yangwei, ZHANG Yan. Numerical research on effects of blade tip clearances onthe hemocompatibility of artificial heart pump[J]. Journal of Aerospace Power, 2021, 36(6): 1304-1314. doi: 10.13224/j.cnki.jasp.2021.06.019
Citation: XIE Nan, TANG Yumeng, LIU Yangwei, ZHANG Yan. Numerical research on effects of blade tip clearances onthe hemocompatibility of artificial heart pump[J]. Journal of Aerospace Power, 2021, 36(6): 1304-1314. doi: 10.13224/j.cnki.jasp.2021.06.019
shu

Numerical research on effects of blade tip clearances onthe hemocompatibility of artificial heart pump

doi: 10.13224/j.cnki.jasp.2021.06.019
  • 1.

    National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics,School of Energy and Power Engineering,Beijing University of Aeronautics and Astronautics,Beijing 100191,China

  • 2.

    Collaborative Innovation Center for Advanced Aero-Engine,Beijing 100191,China

  • 3.

    Department of Cardiac Surgery,Fu Wai Hospital,Chinese Academy of Medical Sciences,Beijing 100037,China

  • Received Date: 2020-08-31
  • Publish Date: 2021-06-28
    Abstract
  • Steady and unsteady numerical simulations were carried out to systematically research the hemodynamic performance and hemocompatibility of four groups of centrifugal blood pumps with different blade tip clearance at 173 mmHg. The gaps studied were 5.0 mm, 2.0 mm, 1.0 mm and 0.2 mm, respectively, the distribution of parameters and the changes of normalized index of hemolysis with the size of blade tip clearance were researched. The results showed that the origin pump had good hemocompatibility at 3.0 L/min against a pressure head of 173 mmHg; with the decrease of blade tip clearance, the max stress and the normalized index of hemolysis showed a single peak and the minimum normalized index of hemolysis 0.000 5 g/100 L was obtained in the 1.0 mm clearance structure, which reduced the risk of thrombosis in the gap between the outer impeller walls and the lower housing cavity walls; compared with the results of the unsteady simulation: steady results were often too small to predict hemolysis, the transient normalized index of hemolysis changed periodically with the impeller rotation, and the difference between its mean and the steady results was within 5%.

     

    • FullText(HTML)
  • loading
    • References(28)
  • [1]
    胡盛寿,高润霖,刘力生,等.《中国心血管病报告2018》概要［J］.中国循环杂志,2019,34(3):209-220. HU Shengshou,GAO Runlin,LIU Lisheng,et al.Summary of the 2018 report on cardiovascular diseases in china［J］.Chinese Circulation Journal,2019,34(3):209-220.(in Chinese)
    [2]
    武文芳,吴兵.人工心脏的历史及研究进展［J］.中国医学装备,2008,5(3):55-58. WU Wenfang,WU Bing.The history and research progress of artificial heart［J］.China Medical Equipment,2008,5(3):55-58.(in Chinese)
    [3]
    ALISON L M,YURI B,CHRISTOPHER C L,et al.Recent ad-vances in computational methodology for simulation of mechanical circulatory assist devices［J］.Wiley Inter-Disciplinary Reviews:Systems Biology and Medicine,2014,6(2):169-188.
    [4]
    MORALES D L,GUNTER K S,FRASER C D.Pediatric mechan-ical circulatory support［J］.International Journal of Artificial Organs,2006,29(10):920-937.
    [5]
    高洁,李建朝,程兆云,等.体外膜氧合辅助9例危重型新型冠状病毒肺炎患者疗效分析［J］.中国体外循环杂志,2020,18(4):203-207. GAO Jie,LI Jianchao,CHENG Zhaoyun,et al.Clinical analysis of COVID－19 patients supported by extracorporeal membrane oxygenation treatment［J］.Chinese Journal of Extracorporeal Circulation,2020,18(4):203-207.(in Chinese)
    [6]
    马纪梅.人工心脏的经皮传能系统的研究［D］.天津:河北工业大学,2011. MA Jimei.Transcutaneous energy transmission system for artificial heart［D］.Tianjin:Hebei University of Technology,2011.(in Chinese)
    [7]
    LIU Yangwei,YAN Hao,LU Lipeng,et al.Investigation of vortical structures and turbulence characteristics in corner separation in a linear compressor cascade using DDES［J］.ASME Journal of Fluids Engineering,2017,139(2):021107.1-021107.14.
    [8]
    LIU Yangwei,ZHONG Luyang,LU Lipeng.Comparison of DDES and URANS for unsteady tip leakage flow in an axial compressor rotor［J］.ASME Journal of Fluids Engineering,2019,141(12):121405.1-121405.13.
    [9]
    云忠.血液机械损伤机理及高速螺旋血泵结构优化研究［D］.长沙:中南大学,2007. YUN Zhong.Research on the mechanical injure principle of blood and on the structure optimization of the high-speed spiral blood pump［D］.Changsha:Central South University,2007.(in Chinese)
    [10]
    云忠,谭建平.基于血液剪切损伤机理的高速螺旋血泵仿真分析［J］.中山大学学报(自然科学版),2008,47(1):47-50. YUN Zhong,TAN Jianping.Simulation analysis of the high-speed spiral blood pump based on the shear injure principle of blood［J］.ACTA Scientiarum Naturalium Universitatis Sunyatseni,2008,47(1):47-50.(in Chinese)
    [11]
    云忠,石芬,向闯,等.混流血泵血液压差损伤机理分析及仿真［J］.机械设计与研究,2010,26(3):29-32,48. YUN Zhong,SHI Fen,XIANG Chuang,et al.Study on the injury principle of the blood prossure differevce in the mixed blood pump and its simulation analysis［J］.Machine Design and Research,2010,26(3):29-32,48.(in Chinese)
    [12]
    云忠,谭建平,龚中良.轴流血泵叶轮结构CFD仿真优化研究［J］.机械设计,2006,23(10):6-9. YUN Zhong,TAN Jianping,GONG Zhongliang.Research of CFD simulative optimization on impeller structure of axial blood pump［J］.Journal of Machine Design,2006,23(10):6-9.(in Chinese)
    [13]
    李卫东.离心式人工心脏泵血流动力学特性分析与优化研究［D］.哈尔滨:哈尔滨工业大学,2016. LI Weidong.Hemodynamic performance analysis and optimization study on centrifugal artificial heart pump［D］.Harbin:Harbin Institute of Technology,2016.(in Chinese)
    [14]
    展昭,张岩,桂幸民.某轴流式血液泵的实验与改进设计［J］.航空动力学报,2008,23(6):1061-1066. ZHAN Zhao,ZHANG Yan,GUI Xingmin.Experiment and design improvement of an axial flow blood pump［J］.Journal of Aerospace Power,2008,23(6):1061-1066.(in Chinese)
    [15]
    杨晓琛,张岩,桂幸民.叶轮式辅助心脏泵装置优化设计［J］.航空动力学报,2011,26(6):1370-1376. YANG Xiaochen,ZHANG Yan,GUI Xingmin.Optimization and design of an impeller assist heart pump device［J］.Journal of Aerospace Power,2011,26(6):1370-1376.(in Chinese)
    [16]
    张岩,薛嵩,桂幸民,等.运用三维数值模拟对人工心脏轴流血泵的设计和改进［J］.中国生物医学工程学报,2007,26(1):35-41. ZHANG Yan,XUE Song,GUI Xingmin,et al.Digital simulation to the development of axial blood pump for artificial heart［J］.Chinese Journal of Biomedical Engineering,2007,26(1):35-41.(in Chinese)
    [17]
    GELLMAN B,DASSE K A,GILBERT R J,et al.Computational and experimental evaluation of the fluid dynamics and hemocompatibility of the centrimag blood pump［J］.Artificial Organs,2006,30(3):168-177.
    [18]
    ZHANG J F,ZHANG P,KATHARINE H,et al.Comparison and experimental validation of fluid dynamic numerical models for a clinical ventricular assist device［J］.Artificial Organs,2013,37(4):380-389.
    [19]
    GHISTA D N,KABINEJADIAN F.Coronary artery bypass grafting hemodynamics and anastomosis design:a biomedical engineering review［J］.BioMedical Engineering OnLine,2013,12(1):1-28.
    [20]
    LIU G M,JIN D H,JIANG X H,et al.Numerical and in vitro experimental investigation of the hemolytic performance at the off-design point of an axial ventricular assist pump［J］.ASAIO Journal,2016,62(6):657-665.
    [21]
    MULHOLLAND J W,SHELTON J C,LUO X Y.Blood flow and damage by the roller pumps during cardiopulmonary by-pass［J］.Journal of Fluids and Structures,2005,20(1):129-140.
    [22]
    FUNG Y C,SKALAK R.Biomechanics:mechanical properties of living tissues［M］.Berlin:Springer-Verlag,1981.
    [23]
    HUANG C R,FABISIAK W.A rheological equation characterizing both the time dependent and the steady state viscosity of whole human blood［J］.American Institute of Chemical Engineers (Symposium Series),1978,74(1):19-21.
    [24]
    BLUDSZUWEIT C.Model for a general mechanical blood damage prediction［J］.Artificial Organs,1995,19(7):583-589.
    [25]
    BLACKSHEAR P L,DORMAN F D,STELNBACH J H.Some mechanical effects that influence hemolysis［J］.Transactions-American Society for Artificial Internal Organs,1965,11:112-117.
    [26]
    GIERSIEPEN M,WURZINGER L J,OPITZ R,et al.Estimation of shear stress-related blood damage in heart valve pros-theses-in vitro comparison of 25 aortic valves［J］.The International Journal of Artificial Organs,1990,13(5):300-306.
    [27]
    GARON A,FARINAS M I.Fast three-dimensional numerical hemolysis approximation［J］.Artificial Organs,2004,28(11):1016-1025.
    [28]
    BLUDSZUWEIT C.Three-dimensional numerical prediction of stress loading of blood particles in a centrifugal pump［J］.Artificial Organs,1995,19(7):590-596.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF(7736.0KB)
    XML

    Article Metrics

    Article views (414) PDF downloads(161) Cited by()
    Proportional views
    Related

    Copyright © 《Journal of Aerospace Power》 All Rights Reserved.

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return