Abstract: Ant colony algorithm(ACA) is a new bionic optimization algorithm developed in recent years.With global and efficient characteristics,it has been applied in discontinuous space successfully.To introduce it to aircraft design field,a high dimensional,multi-objective and multi-restrained ACA for continuous space was built.In an example,it was applied to the multi-objective optimization design of aerodynamic configuration for hypersonic cruise vehicle(HCV).Through comparison with Pareto genetic algorithms(GA),ACA shows its advantage.Finally,from our research work,ACA has great reference values for complex,multidimensional and large-scale optimization problems in aircraft design field.