Abstract: The design scheme of quasi-3D streamline curvature through-flow inverse problem on S2,m stream surface needs to employ the non-viscous control equations with a loss model of the rotor,vaneless diffuser and stator.For developing a loss model in the centrifugal compressor through-flow design code,among several available centrifugal compressor 1D loss models established by previous papers in 1960s-70s,this paper,at first,selected a model proposed by Galvas M.R.as an original model.Secondly,It modified the original model to adapt to the modern quasi-3D computing techniques.Finally,It proposed and applied a new calling method of the loss model in the design process.The newly revised loss model can not only offer relevant losses at each blade row outlet according to various geometry and flow parameters,but also affect the integration of the velocity field through distributing the entropy increment to every computing station.Thus the new loss model satisfies the request of the through-flow method and reflects more closely to the flowfield in centrifugal compressors.The amount of losses estimated by the new model meets the pragmatic engineering requests.It will be verified further by engineering projects or experiments.