Abstract: Heat-fluid-solid coupling and contact thermo-elastic-plastic analysis was carried for a certain turbine blade-disc, and the stress and strain-time course was obtained in this paper.Based on probabilistic Miner's rule and strain field intensity(SFI)approach, the fatigue/creep life of turbine blade-disc was calculated by using K.N.Smith equation and Manson-Succop creep equation.Influential factors to the fatigue and creep were analyzed according to the life prediction results and some advices about utilization and maintenance of the equipment were given.Results in this paper were close to factual state, proving that the method of residual life prediction for the turbine blade-disc is preferably so far.